Disease: Focal glomerulosclerosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VCAN P13611 versican Extracellular structure 1.00 0.497 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TAGLN Q01995 transgelin Cellular structure 8.5E-02 0.540 0.692
SLC12A3 P55017 solute carrier family 12 member 3 Transporter 3.0E-32 0.493 0.808
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
PKD1 P98161 polycystin 1, transient receptor potential channel interacting 1.00 0.493 0.769
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MMRN1 Q13201 multimerin 1 2.1E-25 0.465 0.846
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP14 P50281 matrix metallopeptidase 14 Enzyme 1.00 0.447 0.769
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
KLF4 O43474 Kruppel like factor 4 Nucleic acid binding 1.00 0.449 0.769